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KMID : 0604020130280030218
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Korean Journal of Critical Care Medicine
2013 Volume.28 No. 3 p.218 ~ p.220
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Treatment of Carbon Monoxide Poisoning with Therapeutic Hypothermia
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Lee Young-Hwan
Sohn You-Dong
Park Seung-Min
Lee Won-Woong
Ahn Ji-Yun
Ahn Hee-Cheol
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Abstract
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Carbon monoxide (CO) is a well-known chemical asphyxiant, which causes tissue hypoxia with prominent neurological injury. Therapeutic hypothermia (TH) has been shown to be an effective neuroprotective method in post-cardiac arrest patients. A 26-year-old man presented to the emergency department with severe CO poisoning. On arrival, the patient was comatose. His vital signs were blood pressure, 130/80 mm Hg; heart rate, 126/min; respiratory rate, 26/min; body temperature, 36℃; and O2 saturation, 94%. Initial carboxyhemoglobin was 45.2%. Because there was no available hyperbaric chamber in our local area, he was intubated and treated with TH. The target temperature was 33 ± 1℃ for 24 hours using an external cooling device. The patient was then allowed to reach normothermia by 0.15-0.25℃/hr. The patient was discharged after normal neurological exams on day 11 at the hospital. TH initiated after exposure to CO may be an effective prophylactic method for preventing neurological sequelae.
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KEYWORD
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carbon monoxide, complication, induced hypothermia, poisoning
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